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In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.

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Errors in segregation during cell division can lead to inflammation in daughter cells.

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image: Scientists Destroy Entire Chromosome with CRISPR

Scientists Destroy Entire Chromosome with CRISPR

By Kerry Grens | August 1, 2017

Multiple DNA breaks at either the centromere or the long arm of the mouse Y chromosome cause it to fragment and disappear.

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image: Transparency Now

Transparency Now

By Mary Beth Aberlin | May 1, 2016

Science is messy. So lay it out, warts and all.

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image: Aneuploid Responses

Aneuploid Responses

By Catherine Offord | May 1, 2016

A recent exchange of papers is divided over the evidence for compensatory gene expression among wild strains of aneuploid yeast.

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image: Contributors

Contributors

By Catherine Offord and Kerry Grens | May 1, 2016

Meet some of the people featured in the May 2016 issue of The Scientist.

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image: Meiotic Mysteries

Meiotic Mysteries

By Karen Schindler | May 1, 2016

Understanding why so many human oocytes contain the wrong number of chromosomes

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image: Picturing Inheritance, 1916

Picturing Inheritance, 1916

By Amanda B. Keener | May 1, 2016

This year marks the centennial of Calvin Bridges’s description of nondisjunction as proof that chromosomes are vehicles for inheritance.

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image: A Scrambled Mess

A Scrambled Mess

By Karen Schindler | May 1, 2016

Why do so many human eggs have the wrong number of chromosomes?

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image: AACR Q&A: Angelika Amon

AACR Q&A: Angelika Amon

By The Scientist Staff | April 19, 2016

The aneuploidy expert shares what she has learned at the American Association for Cancer Research annual meeting.

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