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The Scientist

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Two large-scale studies reveal new insights into the genomic characteristics of childhood cancers.

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In response to short DNA fragments, lymphocytes release mitochondrial DNA that helps trigger an immune response.

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image: New Methods to Detect CRISPR Off-Target Mutations

New Methods to Detect CRISPR Off-Target Mutations

By Sandeep Ravindran | March 1, 2018

Researchers have developed a variety of techniques to detect when CRISPR misses the mark.

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image: Eat Yourself to Live: Autophagy’s Role in Health and Disease

Eat Yourself to Live: Autophagy’s Role in Health and Disease

By Vikramjit Lahiri and Daniel J. Klionsky | March 1, 2018

New details of the molecular process by which our cells consume themselves point to therapeutic potential.

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The variation may help explain why stocked salmon don’t fare as well in the ocean.

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Including microbiome composition in predictions of whether a person is obese can significantly improve their accuracy, according to an analysis.

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Gene flow between elephant species was a common feature of their evolutionary history.

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In cooperation with its microbiome, the animal has genetic help in digesting blood and warding off pathogens.

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image: Stem Cell Vaccine Protects Mice From Cancer

Stem Cell Vaccine Protects Mice From Cancer

By Ruth Williams | February 15, 2018

Stem cells and cancer cells have enough molecular similarities that the former can be used to trigger immunity against the latter.

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image: Researchers Produce Alpaca Antibodies Using Yeast

Researchers Produce Alpaca Antibodies Using Yeast

By Catherine Offord | February 14, 2018

With multiple applications in biomedicine, the antibodies can now be made quickly, cheaply, and without the need for an alpaca or one of its relatives.

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