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image: Infographic: Combo Method of Stem Cell Generation

Infographic: Combo Method of Stem Cell Generation

By Ruth Williams | December 1, 2017

Simultaneous exposure to reprogramming and gene-editing plasmids efficiently produces edited pluripotent colonies.

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The switch from maternal factors involves dynamic reprogramming of the zygotic genome.

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New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

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image: The Rising Research Profile of 23andMe

The Rising Research Profile of 23andMe

By Catherine Offord | December 1, 2017

An exploration of the genetics of earlobe attachment is just the latest collaborative research project to come out of the personal genetic testing company.

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Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.

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image: Six-Letter DNA Alphabet Produces Proteins in Cells

Six-Letter DNA Alphabet Produces Proteins in Cells

By Ruth Williams | November 29, 2017

Transcription and translation of DNA containing synthetic base pairs becomes a reality in living cells.

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image: European Research Council Founder, Molecular Biologist Dies

European Research Council Founder, Molecular Biologist Dies

By Catherine Offord | November 20, 2017

Fotis Kafatos, a Greek researcher famous for his work on malaria, has died at age 77.

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image: Man Receives First In Vivo Gene-Editing Therapy

Man Receives First In Vivo Gene-Editing Therapy

By Kerry Grens | November 15, 2017

The 44-year-old patient has Hunter syndrome, which doctors hope to treat using zinc finger nucleases.

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image: Cancer Researcher, Former AACR President Dies

Cancer Researcher, Former AACR President Dies

By Kerry Grens | November 13, 2017

Donald Coffey, a longtime professor at Johns Hopkins University, discovered the nuclear matrix within cells and its role in DNA replication.

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A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro. 

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