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tag mass spectrometry disease medicine

Mass Spectrometry Applications for Proteomics
Jeffrey Perkel | Aug 19, 2001 | 10+ min read
Click to view the PDF file: Proteomic Mass Spectrometry Equipment Courtesy of CiphergenCiphergen's SELDI process, a MALDI variant that includes a surface-based enrichment step Early in the twentieth century, scientists puzzled over the observation that certain elements that were otherwise physically indistinguishable from each other nevertheless exhibited different radioactive decay characteristics. These elements would ultimately come to be known as isotopes, but at the time this concept was
Bear paw dusted in snow
Hibernating Bears Provide Clue to Preventing Serious Clots in Humans
Natalia Mesa, PhD | Apr 13, 2023 | 3 min read
Low levels of the clotting factor HSP47 protect the sleeping giants from blood clots, and the same may be possible for humans and other mammals.
An Introduction to Metabolomics
An Introduction to Metabolomics
Rebecca Roberts, PhD | Oct 17, 2023 | 5 min read
As the closest reflection of biological phenotype, metabolomics provides critical information about human health and disease.
Mapping Brain Proteins
Devika G. Bansal | Feb 1, 2018 | 7 min read
Researchers are using souped-up mass spectrometry to localize proteins within brain cells.
Lipids in the Spotlight
Carina Storrs | Aug 1, 2012 | 8 min read
A guide to studying lipids using mass spectrometry
a mouse moves away from the camera, its left leg caught in a cloth
Scientists Discover New “Superfast” Muscle Fibers in Mouse Limbs
Katherine Irving | Feb 9, 2023 | 4 min read
Fast twitch fibers like these could one day be used to treat diseases like Parkinson’s.
Analytical Chemistry
The Scientist Staff | Oct 2, 1994 | 2 min read
R.J. Cotter, "Time-of-Flight mass-spectrometry for the structural analysis of biological molecules," Analytical Chemistry, 64:1027-39, 1992. Robert J. Cotter (Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore): "As mass spectrometry continues to play an increasing role in the solution of structural biology problems, the time-of-flight (TOF) mass analyzer is receiving particul
Analytical Chemistry
The Scientist Staff | Oct 2, 1994 | 2 min read
R.J. Cotter, "Time-of-Flight mass-spectrometry for the structural analysis of biological molecules," Analytical Chemistry, 64:1027-39, 1992. Robert J. Cotter (Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore): "As mass spectrometry continues to play an increasing role in the solution of structural biology problems, the time-of-flight (TOF) mass analyzer is receiving particul
a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Holly Barker, PhD | Oct 6, 2022 | 3 min read
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.

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