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image: High-Throughput Epigenetics Analyses

High-Throughput Epigenetics Analyses

By Jyoti Madhusoodanan | January 1, 2018

Emerging technologies help researchers draw mechanistic links between metabolism and epigenetic modification of DNA.

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image: New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

By Katarina Zimmer | November 21, 2017

The immunotherapy, which targets CD22 on cancer cells rather than CD19, might prove useful in patients for whom previous T-cell treatments were unsuccessful. 

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image: First CAR T-Cell Therapy Approved in U.S.

First CAR T-Cell Therapy Approved in U.S.

By Shawna Williams | August 30, 2017

The genetically modified blood cells will be used for patients with a type of acute lymphoblastic leukemia, when other treatments fail.

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image: Immunotherapy Promising for Diabetes: Study

Immunotherapy Promising for Diabetes: Study

By Aggie Mika | August 9, 2017

A small clinical trial demonstrates that peptide immunotherapy can halt the progression of early-stage type 1 diabetes.

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image: The Ever-Expanding T-Cell World: A Primer

The Ever-Expanding T-Cell World: A Primer

By Ashley P. Taylor | August 7, 2017

Researchers continue to identify new T-cell subtypes—and devise ways to use them to fight cancer. The Scientist attempts to catalog them all.

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image: T Cells That Drive Toxic Shock in Mice Identified

T Cells That Drive Toxic Shock in Mice Identified

By Ashley Yeager | June 20, 2017

Overzealous activity by mucosa-associated invariant T (MAIT) cells in response to bacterial toxins can lead to illness instead of stopping it.

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image: Gene Mutations Foretell Immunotherapy Response

Gene Mutations Foretell Immunotherapy Response

By Aggie Mika | June 12, 2017

A drug that blocks an immune checkpoint protein effectively treats tumors in patients with deficient DNA repair genes. 

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image: Pinpointing the Culprit

Pinpointing the Culprit

By Rachel Berkowitz | June 1, 2017

Identifying immune cell subsets with CyTOF

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image: Image of the Day: Lights, Camera, T Cells!

Image of the Day: Lights, Camera, T Cells!

By The Scientist Staff | May 30, 2017

The fluid motions of a T cell’s microvilli, scanning their environment for antigens, are captured in 3-D and in real time.

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image: Gel Scaffolds for Delivery of Immunotherapies

Gel Scaffolds for Delivery of Immunotherapies

By Rachel Berkowitz | April 1, 2017

Using biocompatible polymers to carry cancer immune therapies directly to the tumor

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