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tag kin selection culture immunology

The Jon Yewdell Selection
Jon Yewdell | Apr 6, 2003 | 3 min read
My Top 5 | The Jon Yewdell Selection Courtesy of Jon Yewdell 1. In the now distant year of 1970, the physical nature of the plasma membrane (or any membrane for that matter) was uncertain. Frye and Edidin used Sendai virus to fuse human and mouse cell, then stained the cells with fluorochrome-labeled antibodies specific for human or mouse antigens.1 They watched the unfolding drama in a fluorescent microscope as the human and mouse proteins completely mixed in real time, providing an elega
Immune System Maintains Brain Health
Amanda B. Keener | Nov 1, 2016 | 10+ min read
Once thought only to attack neurons, immune cells turn out to be vital for central nervous system function.
Guts and Glory
Anna Azvolinsky | Apr 1, 2016 | 9 min read
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.
Top 10 Innovations 2021
2021 Top 10 Innovations
The Scientist | Dec 1, 2021 | 10+ min read
The COVID-19 pandemic is still with us. Biomedical innovation has rallied to address that pressing concern while continuing to tackle broader research challenges.
2020 Top 10 Innovations
The Scientist | Dec 1, 2020 | 10+ min read
From a rapid molecular test for COVID-19 to tools that can characterize the antibodies produced in the plasma of patients recovering from the disease, this year’s winners reflect the research community’s shared focus in a challenging year.
Picking a Needle out of a Haystack
Laura Defrancesco | Dec 6, 1998 | 3 min read
Gel Microdrop System from One Cell Systems can ferret out rare protein secreting cells Imagine, if you will, a single cell suspended in a drop. Now picture that same cell secreting a protein, say an immunoglobulin. Now envision that secreting cell embedded in a matrix that binds the protein as it leaves the cell, and you have the idea of the microdrop hybridoma selection system available from One Cell Systems. A modification of the microdrop technology described in 1991 by James Weaver, Associ
The Search for Persisters
Amanda B. Keener | Aug 11, 2015 | 4 min read
Lyme disease–causing bacteria can outmaneuver antibiotics in vitro and manipulate the mouse immune system.
Articles Alert
Simon Silver | Jul 8, 1990 | 7 min read
The Scientist has asked a group of experts to comment periodically upon recent articles that they have found noteworthy. Their selections, presented herein every issue, are neither endorsements of content nor the result of systematic searching. Rather, the list represents personal choices of articles the columnists believe the scientific community as a whole may also find interesting. Reprints of any articles cited here may be ordered through The Genuine Article, 3501 Market St., Philadelphia,
Macrophages Play a Double Role in Cancer
Amanda B. Keener | Apr 1, 2018 | 10+ min read
Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.
Flow Cytometry On-a-Chip
Jeffrey M. Perkel | Jun 1, 2015 | 7 min read
Novel microfluidic devices give researchers new ways to count and sort single cells.

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