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image: Researchers Make Knockout Stem Cell Lines in One Step

Researchers Make Knockout Stem Cell Lines in One Step

By | December 1, 2017

Combining gene editing and stem-cell induction improves efficiency of functional genetic analyses.

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image: Infographic: Combo Method of Stem Cell Generation

Infographic: Combo Method of Stem Cell Generation

By | December 1, 2017

Simultaneous exposure to reprogramming and gene-editing plasmids efficiently produces edited pluripotent colonies.

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Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.

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image: Image of the Day: Purple Podocytes

Image of the Day: Purple Podocytes

By | May 11, 2017

Using human induced pluripotent stem cells, scientists grew podocytes, cells that attach to the kidney's glomeruli and help filter blood.  

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image: New Resource for Banked iPSCs

New Resource for Banked iPSCs

By | May 11, 2017

Researchers describe hundreds of induced pluripotent stem cell lines from healthy individuals. 

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image: Developing Brains in Dishes

Developing Brains in Dishes

By | April 26, 2017

Two studies report methods to mimic human fetal brain development using neurons derived from human induced pluripotent stem cells that form 3-D, brain-like structures. 

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image: Regulators OK Clinical Trials Using Donor Stem Cells

Regulators OK Clinical Trials Using Donor Stem Cells

By | February 6, 2017

Japanese health officials approve human experiments to treat macular degeneration with a cell therapy derived from induced pluripotent stem cells.

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Removing a specific miRNA from stem cells may induce the expression of endogenous retroviruses that enable the cells to form extra-embryonic lineages.

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image: Donor Stem Cells Improve Cardiac Function

Donor Stem Cells Improve Cardiac Function

By | October 12, 2016

After a heart attack, monkeys given induced pluripotent stem cell–derived cardiomyocytes show more regeneration in the organ, but with risks.

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image: Stem Cells Made Waves in Biology and Medicine

Stem Cells Made Waves in Biology and Medicine

By | October 1, 2016

Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.

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