Flavivirus infections alter the skin microbiome of mice to increase the production of a sweet-smelling compound that attracts the viruses’ insect vectors, a study finds.
Previous flavivirus infection could help explain the severity of symptoms in some people infected during the ongoing Zika outbreak, researchers report.
By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.