Metformin and lipodystrophy

NEW YORK, 26 July (Praxis Press) The human immunodeficiency virus (HIV) lipodystrophy syndrome is characterized by fat redistribution and insulin resistance; this syndrome is particularly common among patients receiving combined antiretroviral therapy. Hadigan and colleagues studied the safety and efficacy of metformin in patients with the HIV lipodystrophy syndrome. Low-dose metformin treatment decreased body mass index and abdominal fat, improved hyperinsulinemia, and lowered diastolic blood p

July 27, 2000

NEW YORK, 26 July (Praxis Press) The human immunodeficiency virus (HIV) lipodystrophy syndrome is characterized by fat redistribution and insulin resistance; this syndrome is particularly common among patients receiving combined antiretroviral therapy. Hadigan and colleagues studied the safety and efficacy of metformin in patients with the HIV lipodystrophy syndrome. Low-dose metformin treatment decreased body mass index and abdominal fat, improved hyperinsulinemia, and lowered diastolic blood pressure. No serious adverse effects were noted; mild diarrhea was the most common minor adverse effect. Low-dose metformin is an effective and well-tolerated treatment for HIV lipodystrophy.

Popular Now

  1. A Newly Identified Species Represents Its Own Eukaryotic Lineage
  2. Telomere Length and Childhood Stress Don’t Always Correlate
  3. Optogenetic Therapies Move Closer to Clinical Use
  4. Research Links Gut Health to Neurodegeneration
    The Nutshell Research Links Gut Health to Neurodegeneration

    Rodent studies presented at the Society for Neuroscience meeting this week tie pathologies in the gastrointestinal tract or microbiome composition with Parkinson’s and Alzheimer’s diseases.

RayBiotech