Inflammation, Pain, and Resolvins

Not all inflammation leads to pain. Despite widespread infection followed by fever, colds rarely cause pain. But when some cytokines and certain immune cells are active near pain-sensing nerves, they trigger receptors that convey pain sensations to the brain.

By | January 1, 2012

Infographic: Inflammation, Pain, and Resolvins
View PDFs PDF
LUCY READING-IKKANDA

Not all inflammation leads to pain. Despite widespread infection followed by fever, colds rarely cause pain. But when some cytokines and certain immune cells are active near pain-sensing nerves, they trigger receptors that convey pain sensations to the brain. Resolvins are naturally produced part-way into an inflammatory reaction, and help diminish inflammation as well as pain. Chronic pain is a complicated disorder that can be influenced as much by mood and personal experience as it can by persistent inflammation or unresolved pain. In some cases when pain is constantly relayed through the peripheral nerves to the central nervous system, a sort of imprint or pain memory is created, leading to chronic pain. Resolvins can dampen the nerve transmission that leads to chronic pain by acting both at the peripheral nerve and in the spine.

Read the full story.

Add a Comment

Avatar of: You

You

Processing...
Processing...

Sign In with your LabX Media Group Passport to leave a comment

Not a member? Register Now!

LabX Media Group Passport Logo

Popular Now

  1. That Other CRISPR Patent Dispute
    Daily News That Other CRISPR Patent Dispute

    The Broad Institute and Rockefeller University disagree over which scientists should be named as inventors on certain patents involving the gene-editing technology.

  2. How Gaining and Losing Weight Affects the Body
    Daily News How Gaining and Losing Weight Affects the Body

    Millions of measurements from 23 people who consumed extra calories every day for a month reveal changes in proteins, metabolites, and gut microbiota that accompany shifts in body mass.

  3. Neurons Use Virus-Like Proteins to Transmit Information
  4. DOE-Sponsored Oak Ridge National Laboratory to Cut 100 More Jobs
AAAS