Pitfalls Associated with Cell Contamination, Misidentification and Authentication

Listen to a discussion of recent efforts that are underway to eradicate cell contamination and misidentification.

By | October 4, 2012

Listen to a discussion of recent efforts that are underway to eradicate cell contamination and misidentification.

Cultured cells are used extensively in research, manufacturing, and for therapeutic purposes. Unfortunately, a large number of cell lines are mislabeled, contaminated, and misidentified, leading to results that are non-replicable, data that is erroneous, and conclusions that are faulty. These problems have often gone unnoticed and unchecked, costing labs a significant amount of time, money, and labor. The authentication of cell lines is a crucial quality-control step, and this webinar's experts will elaborate on some of the recent efforts underway to eradicate these problems.

Human Cell Line Cross-Contamination: 60 Years of Bad Practice, Ignorance, and Fraud

Dr. John Masters, Professor of Experimental Pathology, University College London; Director, Prostate Cancer Research Centre

Topics to be covered:

  • Overview and history of cell authentication
  • Current challenges and solutions
  • Examples and case studies

 

Analytical Approaches to Authentication and Special Issues for Cells Intended for Clinical Use

Dr. Glyn Stacey, Head, Division of Cell Biology and Imaging; Director, UK Stem Cell Bank, National Institute for Biological Standards and Control Cancer Research Centre

Topics to be covered:

  • Analytical Techniques used for cell authentication
  • Approaches for non-human cell lines
  • Issues for identification of cell lines for clinical applications

 

Turning the Tide: Resources to Reduce Cross-Contamination and Avoid Misidentified Cell Lines

Dr. Amanda Capes-Davis, Founding Manager and Honorary Scientist, CellBank Australia; Chair, International Cell Line Authentication Committee (ICLAC)

Topics to be covered:

  • The KB cell line story: why a new initiative is needed
  • The database of cross-contaminated or misidentified cell lines
  • The International Cell Line Authentication Committee (ICLAC)

Watch the webinar now!

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Comments

Avatar of: Yes

Yes

Posts: 1

October 19, 2012

Honored to be part of i fucking love science. Thanks for the good work.

Avatar of: Joao Leal

Joao Leal

Posts: 1

October 19, 2012

Thank you to " I fucking love Science" to bring me here.

Avatar of: Tony K

Tony K

Posts: 1

October 24, 2012

Thank you for a great presentation and providing great insight on what needs to be done and why. This was important to clarify the need for CLA and Mycoplasma testing. Thanks again for selecting this topic and highlighting the importance of STR profiling to ensure that you are working with a clean cell line.

Avatar of: JP Dangy

JP Dangy

Posts: 1

January 7, 2013

The quality of the slides and the sound is really poor the use of such bad software doesn't give justice to teh great presentations of teh invited speakers you rather should use Quick Time and encodes sound and vidéo in HD

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