After implantation, the tissue developed blood vessels and became integrated into neuronal networks in the animals’ brains.
How brains of toddlers with autism respond to language is associated with later cognitive abilities.
May 31, 2013|
Children with autism show a variety of linguistic and social abilities, and it can be difficult to predict how a child will develop. But monitoring brain activity in 2-year-olds with autism spectrum disorder (ASD) can help predict their cognitive abilities at ages 4 and 6, according to a study published yesterday (May 29) in PLOS ONE.
Patricia Kuhl of the University of Washington and colleagues recruited 24 2-year-olds with ASD and 20 children of the same age who were developing normally. The researchers measured electrical activity in the children’s brains with noninvasive electroencephalography. The researchers then read the children both familiar and unfamiliar words, which the children’s parents helped the researchers determine.
When the developmentally normal children heard unfamiliar words, the electrical activity in their brains’ left hemisphere spiked in a predictable pattern. Some of the children with ASD, however, showed greatly diminished brain responses to the unfamiliar words, while others showed more normal responses.
When the children with ASD underwent cognitive tests at age 4, the ones who showed more normal brain responses to the unfamiliar words had higher cognitive abilities. When the researchers tested the children again at age 6, children whose brains had responded to the unfamiliar words showed an even greater advantage.
Moreover, even at age 2, the children who had more normal responses to unfamiliar words were likely to have higher scores on tests of social cognition.
“This information could be used to tailor treatment interventions from earlier ages than currently possible with behavior alone,” Elizabeth Redcay, a neuroscientist at the University of Maryland, College Park, told ScienceNOW.
The findings also support the idea that social skills are related to the acquisition of language and that low social cognition could help explain some autism patients’ difficulty with language.
Kuhl told Time that she plans to trying the test on 14-month-olds in hopes of predicting problems with language even earlier.