A recent toast to James Watson highlights a tolerance for bigotry many want excised from the scientific community.
The drug has brought relief to children suffering from cancer and other serious ailments, but getting access is often limited by considerable regulatory hurdles.
July 17, 2013|
WIKIMEDIA, LAURIE AVOCADOLauren Scott has been fighting undifferentiated soft tissue sarcoma, a rare and aggressive form of cancer, for more than 3 years. After a brief period of remission, Lauren’s cancer, in recent months, spread to her lungs, where a large and inoperable tumor makes daily activity, and sometimes breathing, difficult.
When morphine could not ease her pain without causing severe nausea, Lauren turned to marijuana for relief. She is 16 years old.
Her mother, Cherri Chiodo, says medical cannabis—which for Lauren comes in the form of an oil that is especially rich in cannabidiol (CBD), the chemical that contains much of marijuana's medicinal properties, and low in THC (tetrahydrocannabinol), the psychoactive chemical that makes people “high”—is “the only thing that helps.” While the drug is primarily used to manage Lauren’s pain, Chiodo noted it also helps stimulate Lauren’s appetite and reduce the “anxiety that comes from facing a terminal cancer.”
Eighteen states and the District of Columbia have legalized the use medical marijuana in patients with qualifying medical conditions—from cancer to chronic pain—and all but two of those jurisdictions permit its use in children. But even in jurisdictions that have green-lighted its use in children, accessing the drug is not always easy.
In addition to a doctor’s stamp of approval, all permitting states require some form of parental consent for medical marijuana use in kids. Some states have additional red-tape in place, such as requiring more than one doctor to sign off on a prescription or banning dispensaries from selling edible forms of medical marijuana, such as “pot brownies” and other baked goods made with drug, which some lawmakers fear are more likely to be misused or abused by adolescents.
On June 24, however, the New Jersey Legislature passed a bill that would make it easier for minors to receive medical marijuana, a move advocates believe is signaling a larger change. “People want access to natural and safer remedies—for themselves and for their children,” said Paul Armentano, deputy of NORML, a non-profit organization that lobbies for the reform of prohibitive marijuana laws.
The New Jersey bill was inspired by Vivian Wilson, a 2-year old with a rare and severe form of epilepsy, whose seizures have been drastically reduced through medical marijuana use. If Governor Chris Christie signs the bill into law, it would reduce the number of doctor approvals that minors need for access to just one, the same as the requirement for adults. In addition, ingestible forms of medical marijuana, such as lozenges, would become available, making it easier for children to take the drug.
In Nevada, where Chiodo and Lauren live, medical marijuana users currently have no way to safely and legally access the drug without growing it themselves. But thanks to a new law passed by State Governor Brian Sandoval that legalizes medical marijuana dispensaries in the state, that will soon change. In the next year, more than 25 state-regulated medical marijuana dispensaries are expected to open.
Until then, an anonymous grower provides Lauren with a free supply of her cannabis oil. Each day, Lauren takes up to a gram of the oil that her mother funnels into capsules or adds to her food.
But with limited safety and efficacy data on medical marijuana use in adults, never mind in children, there are still big questions in the medical community about if and when to prescribe the drug. Some doctors, however, swear by its use. Dustin Sulak, an osteopathic general practitioner in Falmouth, Maine, uses medical marijuana to treat children who have cancer or other serious conditions, including seizure disorders, autism, and post-traumatic stress disorder, when conventional treatments have failed. “We put all the options on the table and evaluate the risk/benefit ratio of each,” said Sulak. “[Medical marijuana] often emerges as a good choice because of its tolerability and efficacy.”
Gregory Carter, a professor at the University of Washington School of Medicine and a clinician specializing in neuromuscular diseases, has also recommended medical marijuana for children with severe neurological disorders, such as cerebral palsy and childhood muscular dystrophy, and has seen “mostly positive” results.
Sulak and Carter say they have prescribed the drug not only for symptom relief, but also for its potential therapeutic effect. Cannabinoids, a chemical compound found in the cannabis plant, have been shown to stimulate the body’s endocannabinoid system, an important physiological system involved in the regulation of appetite, pain-sensation, and mood. Cannabinoids have also been shown to directly inhibit tumor growth and metastases in vitro and in animal tumor models, suggesting the endocannabinoid system may hold promise as a therapeutic target in cancer. Of course, because marijuana has not been put through the U.S. Food and Drug Administration approval process, very few reliable studies demonstrate its efficacy—none of them in children.
Furthermore, marijuana is illegal at the federal level and some doctors say it should not be used by adults, let alone children. The American Academy of Pediatrics, for one, has raised questions surrounding the uncertainty of medical marijuana’s effects on children’s still-developing brains and nervous systems.
Unfortunately, the dearth of data on marijuana’s safety and effectiveness is not likely to grow anytime soon. The federal government classifies marijuana as a Schedule I drug, which means it cannot be easily studied in humans for medical value.
But advocates of the drug argue that it must be compared on a case-by-case basis with the other available options, which in many cases “are much more toxic,” says Sulak. Like marijuana, most of the alternatives currently given to children with cancer, such morphine and oxycontin, and powerful antipsychotic drugs that are used in long-term treatment of childhood mental illnesses have not been studied for either safety or efficacy in children. In fact, fewer than half of all drugs routinely used to treat children have been studied in pediatric trials.
And anecdotally, at least, marijuana appears to be relatively safe and well-tolerated by children. “The nice things about cannabis is that the negative side effects are much less than most other drugs given to children,” Sulak said. Carter agreed: “I do feel, under almost any circumstance, that medial marijuana is safer than opioids.”
Both, however, note that instances in which they have prescribed medical marijuana are extremely rare, as is the case nationwide. Most states where medical marijuana is legal do not keep demographic data on its registrants, but those that do demonstrate medical marijuana usage among children is limited. Colorado, for instance, currently counts 45 children on the state’s medical marijuana registry that have taken medical cannabis, while Montana reports 55. In Nevada, Lauren is the state’s only medical marijuana registrant under the age of 18.
“If you look at the numbers, you can see this is not a situation where suddenly you will have thousands upon thousands or even hundreds upon hundreds of children using marijuana,” said Armentano. “It should be available to the small number of children who do need it.”
July 18, 2013
You would think that we would want to encourage research by changing the scheduling of marijuana. But our Nation's anti-science posture makes this illegal. This is due to some sort of ethnic bias, fears of change, and residual hatred of anti-Vietnam war protesters. Read about the exisint laws here;
"Advocates of marijuana legalization argue that the budgetary impact of removing cannabis from Schedule I of the Controlled Substances Act and legalizing its use in the United States could save billions by reducing government spending for prohibition enforcement in the criminal justice system. Additionally, they argue that billions in annual tax revenues could be generated through proposed taxation and regulation. Patient advocates argue that by reclassifying marijuana, millions of Americans who are currently prevented from using medical marijuana would be able to benefit from its therapeutic value."
Or we can continue with the witch hunt and pay to imprison working tax paying Americans.
July 18, 2013
The US Government is well aware of the effacey of cannabis. It's listed in the patent they have on it.
In today's medical science:
there is a reported 25% decrease in dementia over twenty years.
Now that the statistics of reduced dementia are verifiable it’s really not that difficult to discern that today’s elderly (baby boomers) use cannabis at about the same rate as the the decrease.
The US government has patented the cannabinoids in cannabis Us patent #6630507 the patent abstract states:
Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and HIV dementia. Nonpsychoactive cannabinoids, such as cannabidoil, are particularly advantageous to use because they avoid toxicity that is encountered with psychoactive cannabinoids at high doses useful in the method of the present invention. A particular disclosed class of cannabinoids useful as neuroprotective antioxidants is formula (I) wherein the R group is independently selected from the group consisting of H, CH.sub.3, and COCH.sub.3. ##STR1##
It’s a shame we have a government that knows there's a cure for dementia, but has a war on it’s citizenry using it.
July 28, 2013
The biggest obstacle to change is the association with seriously hard drugs like the opiates and cocaine. There is also the 'cash cow', that huge investment in law enforcement with its jobs, materials, endless equipment, vehicles, etc.. Then too the secondary 'cash cow' of private prisons where more inmates equals greater profit. Of course there are the lawyers. These 'cows' don't die easily. Compare Big Oil to alternative energy to see how once capitalism is in the sweet spot, is not going to simply relinquish the position. There is adaquate evidence that Cannabis is useful and the hope is,reasonable people in positons of power will make proper choices.
August 14, 2013
There's a bit of a move afoot in Latin and South America to "decriminalize" marijuana. No idea if kids feature in any of this legislation but either way this could create a real medical tourism boom for any one of them that decides to market their new law this way. b
February 28, 2014
its stupid how they dont focus on thc's benefits even though its labelled as getting high if there was no thc in marijuana it would not help me with serious anxiety i know this because ive tried cbd oil while calming and relaxing pain relieving its not the same as smoking a joint or bong and getting instant relief and feeling calm and allowing me to be social etc. but whatever at least they take some interest into one part of the plant