TB Vaccine Protects Against MS

A vaccine developed to ward off tuberculosis may help prevent symptoms of multiple sclerosis, according to a new study.

By | December 10, 2013

FLICKR, DANIEL PAQUETPatients with early signs of multiple sclerosis (MS) may benefit from the bacille Calmette-Guerin (BCG) vaccine for tuberculosis (TB), according to a study published last week (December 4) in Neurology.

The vaccine may prove to be “safe, inexpensive, and handy” in the treatment of MS, suggest the authors, led by Giovanni Ristori of the Center for Experimental Neurological Therapies at Sant'Andrea Hospital in Rome.

The trial involved 82 people whose MRI scans were suggestive of MS and who had experienced numbness or vision or balance problems—a condition called clinically isolated syndrome that, about half the time, leads to full-blown MS within two years. Six months later, those who received the BCG vaccine had fewer brain lesions than did those given placebo. Moreover, after five years of being treated with MS drugs such as interferon beta-1a (Avonex), 58 percent of vaccinated patients experienced no further MS episodes, compared with 30 percent of those who received the placebo.

“The interesting thing was that the single injection affected the course of the recipients for up to five years after they received it,” Dennis Bourdette, the chairman of neurology at Oregon Health & Science University who coauthored an accompanying Neurology editorial, told Bloomberg.

The BCG is also being tested for in patients with Type 1 diabetes, according to The Washington Post.

Add a Comment

Avatar of: You

You

Processing...
Processing...

Sign In with your LabX Media Group Passport to leave a comment

Not a member? Register Now!

LabX Media Group Passport Logo

Popular Now

  1. Thousands of Mutations Accumulate in the Human Brain Over a Lifetime
  2. 2017 Top 10 Innovations
    Features 2017 Top 10 Innovations

    From single-cell analysis to whole-genome sequencing, this year’s best new products shine on many levels.

  3. Search for Life on the Red Planet
  4. Two Dozen House Republicans Do an About-Face on Tuition Tax
FreeShip