Neuro-Insights into Holding It

Scientists reveal the neural underpinnings—and muscles tightly linked with—the involuntary flexing of the pelvic floor, which comprises muscles that help us delay urination.

By | October 17, 2014

FLICKR, MIKE LICHTResearchers at the University of Southern California (USC) and Loma Linda University incidentally discovered the parts of the brain that control the tightening of the all-important, pee-holding pelvic floor muscles, and identified a number of other muscles throughout the body that flex in concert, according to a study published earlier this month (October 8) in the Journal of Neuroscience.

“We knew that pelvic floor muscles contract involuntarily in healthy people to make sure they don’t accidently urinate, but we didn’t know what part of the nervous system was doing this,” coauthor Jason Kutch, an assistant professor in the Division of Biokinesiology & Physical Therapy at the USC Ostrow School of Dentistry, said in a press release. “Now we know that there are specific brain regions controlling involuntary pelvic floor contraction.”

Kutch and his colleagues were studying chronic abdominal and pelvic floor pain when they discovered the muscular and neural correlates of pelvic floor clenching. Using electromyography (EMG) to measure muscle activation, the team showed tightening in diverse muscles—including the glutes and those in the toes—also results in pelvic floor flexing. Functional MRI further revealed that the medial wall of the precentral gyrus, a brain region in the primary motor cortex, correlates with the activation of both the pelvic floor and the associated muscle groups. Flexing of the fingers, on the other hand, did not trigger pelvic floor flexing or medial wall activation.

“We hope that this vein of research will help us to find the causes of chronic pelvic floor pain, which disproportionately affect women, and may even yield information that could help people struggling with incontinence,” Kutch said.

Add a Comment

Avatar of: You



Sign In with your LabX Media Group Passport to leave a comment

Not a member? Register Now!

LabX Media Group Passport Logo

Popular Now

  1. Man Receives First In Vivo Gene-Editing Therapy
  2. Researchers Build a Cancer Immunotherapy Without Immune Cells
  3. Research Links Gut Health to Neurodegeneration
    The Nutshell Research Links Gut Health to Neurodegeneration

    Rodent studies presented at the Society for Neuroscience meeting this week tie pathologies in the gastrointestinal tract or microbiome composition with Parkinson’s and Alzheimer’s diseases.

  4. Long-term Study Finds That the Pesticide Glyphosate Does Not Cause Cancer