A few months after the American Chemical Society won its lawsuit against the pirate site, the game of virtual whack-a-mole continues.
November 2014's selection of notable quotes
November 1, 2014|
JG MARCELINO/WEBS R US/WIKIMEDIA COMMONS
—University of Virginia neuroscientist Barry Condron, opining on the promise of neuroscience research (The Cavalier Daily, October 10)
—Colin Lever, a senior lecturer in the department of psychology at Durham University in the U.K., speaking to The Scientist about the Nobel Prize recently awarded to his mentor John O’Keefe and to May-Britt and Edvard Moser for discovering cells that constitute the brain’s GPS system (October 6)
—Neurologist and author Oliver Sacks, in his 2010 book The Mind’s Eye, in which he discusses his struggles with prosopagnosia, or face blindness
—Sally Rockey, the National Institutes of Health’s Deputy Director for Extramural Research, on the agency’s plan to develop and implement policies requiring NIH applicants to consider sex as a variable in biomedical research involving animals and cells (September 11)
—Sebastian Funk, researcher at the Centre for the Mathematical Modelling of Infectious Diseases, and Peter Piot, London School of Hygiene and Tropical Medicine microbiologist and codiscoverer of the Ebola virus, in a recent eLife paper about mapping the disease in wild African animals (September 19)
—The ill-advised, post-sneeze joke voiced by an as-yet-unnamed man who was escorted off of his flight by health workers wearing full hazmat suits in Punta Cana, Dominican Republic (October 10)
November 5, 2014
The quotes are scattered from across disciplines, but can be linked to what is known about conserved molecular mechanisms of biologically-based cause and effect that, in context, make sense of them.
1) Cell type differentiation occurs via amino acid substitutions in the Ebola viruses. Identification of two amino acid residues on Ebola virus glycoprotein 1 critical for cell entry
2) What is known about nutrient-dependent pheromone-controlled sex differences in cell type differentiation via amino acid substitutions appears to extend from non-living viruses to the differentiation of all cell types in all individuals of all species.
4) Place it into the context of "The Mind's Eyes: Human pheromones, neuroscience, and male sexual preferences."
5) It should come as no surprise to learn that ecological variation leads to ecological adaptations manifested in the connectome and in unconsciuos affects associated with face perception and cognition. Arguably, the only pathway that links the epigenetic landscape to the physical landscape of DNA in the organized genomes of species from microbes to man is the gene-cell-tissue-organ-organ system pathway.
6) We used that pathway in our 2001 review Human pheromones: integrating neuroendocrinology and ethology.
7) Panksepp et al, (2002) followed with Comparative approaches in evolutionary psychology: molecular neuroscience meets the mind.
Unless excitatory amino acid transporters somehow evolved due to mutations, they appear to exemplify how nutrient-uptake and the pheromone-controlled physiology of reproduction link ecological, social, neurogenic, and socio-cognitive niche construction. Niche constuction links increasing organismal complexity based on what is known about conserved molecular mechanisms that link physics to the chemistry of protein folding and RNA-mediated events. The RNA-mediated events link the Ebola viruses to human ignorance of biophysically-constrained cause and effect.
It is often attributed to mutations and/or natural selection that somehow leads to the evolution of biodiversity and "Excitatory amino acid transporters" in the context of the connectome via cell type differentiation in our brain.
November 6, 2014
I doubt that knowing and understanding all the connections in a brain would prefectly predict behavior. Many threshold level events in signaling are probabilistic, and this rigidly deterninistic statement does not take this into account. I suspect that more of our behavior is random than we'd like ot believe.