Another CAR-T IPO

Cellectis goes public for a whopping $228 million—nearly double the value the company filed for in February.

By | April 6, 2015

FLICKR, REYNERMEDIAThe Paris-based biotech Cellectis has joined a handful of other companies in going public with its chimeric antigen receptor (CAR) T-cell therapies, grossing more than $228 million in its initial public offering (IPO) on the Nasdaq last month (March 24). That value is $113 million more than the company initially filed for a month earlier, and makes it the second largest IPO in the CAR T space; Juno Therapeutics has retained the number-one spot with its $265 million IPO last December.

CAR T-cell therapies are a hot field, with dozens of organizations, including a handful of big pharma companies, working to develop T cells armed with receptors that bind particular cancer-associated antigens. In the last couple of years, hundreds of millions of dollars’ worth of deals have been struck, and dozens of clinical trials initiated. (Read more about the field in this month’s biobusiness article, “The CAR T-Cell Race.”)

Cellectis’s focus is on allogeneic T cells, or those taken from donated samples, in hopes of making an off-the-shelf therapy that can be more widely used than autologous cells. The company got a boost last year when it struck a deal with Pfizer for $80 million up front, plus up to $185 million per product and royalties. In its new IPO, Cellectis priced 5.5 million American shares at $41.50 each, with another 825,000 shares set away for the company’s underwriters. The money will go toward advancing four CAR-T candidates through Phase 1 trials, manufacturing the therapies, and work outside of oncology.

(Hat tip: Fierce Biotech)

Add a Comment

Avatar of: You



Sign In with your LabX Media Group Passport to leave a comment

Not a member? Register Now!

LabX Media Group Passport Logo

Popular Now

  1. 2017 Top 10 Innovations
    Features 2017 Top 10 Innovations

    From single-cell analysis to whole-genome sequencing, this year’s best new products shine on many levels.

  2. Thousands of Mutations Accumulate in the Human Brain Over a Lifetime
  3. Antiviral Immunotherapy Comes of Age
    News Analysis Antiviral Immunotherapy Comes of Age

    T-cell therapies are not just for cancer. Researchers are also advancing immunotherapy methods to protect bone marrow transplant patients from viral infections. 

  4. Search for Life on the Red Planet