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Zebrafish hair cells regrow via cyclin gene activity in specific cells, offering clues to future hearing restoration in humans.

A fungal pathogen has rendered the Southern corroboree frog functionally extinct. Can genomics technologies pull the species back from the brink?

A new study identified Parkinson’s disease-associated compounds from earwax, but some scientists remain skeptical.

Current CRISPR guide RNAs are designed based on European reference genomes, leading to false-negative results in cells from people with African ancestry.

In a model of chronic NAD+ depletion that mimics aging, mitochondria are revealed as a rheostat of cellular NAD+ levels.

New research suggests that long-distance running triggers a temporary change in brain structure.

The Scientist is excited to announce the winners of our 2025 science writing contest!

New research helps unlock the secret to staying safe from wildfire smoke.

A genetically diverse mouse model allowed researchers to identify genes that promote the success of immune checkpoint inhibitors against cancer.

Microbiomes in older mice pumped out damaging metabolites that drove endothelial cell senescence, offering potential targets for therapeutic intervention.

Scientists identified the mechanism by which a sea cucumber molecule inhibits sulfatase-2, an enzyme that’s often upregulated in cancer.

Distinct microRNA signatures in the saliva of people with endometriosis provide a basis for a non-invasive diagnostic test and shed light on disease biology.

Absence of cysteine in mice coaxed fat-storing cells to burn energy, causing weight loss and offering potential therapeutic targets to improve metabolic health.

A receptor on macrophages dictated their ability to reduce inflammation after liver transplant, offering potential therapeutic targets to avoid complications.

Molecules that build coenzyme Q10, vital for mitochondrial function, healed mice and a patient with an ultra-rare and lethal neurodevelopmental disorder.

As early-onset cancers rise, more people are faced with the question of how their treatment might affect their ability to have children.

Plant biotechnologists are favoring moss factories over other models to produce certain valuable proteins.

Tickling is a strange and intriguing sensation. It’s one that scientists are still working to fully explain.

Collagen IV provides crucial structural support for cells and tissues, but it’s unstable at body temperature. Researchers now identified how it stays together.

After years of debate, scientists provided new evidence for the lifelong birth of human brain cells, which may inform future therapies for neurological diseases.