Image of the Day: Unseen Trauma

Pressure from simulated blast waves, similar to those generated by explosives, induced molecular markers of stress and injury within mouse retinas.

By | June 20, 2017

Immunofluorescent image of a retina from a mouse subjected to blast wave pressure. Glial fibrillary acidic proteins (green), indicating glial cell activation, and pathology-associated phosphorylated tau (red) are coexpressed in glial cells (yellow).
    "Our results may explain symptoms of visual dysfunction reported by combat veterans who have experienced [traumatic brain injury]," says senior author Heather West Greenlee of Iowa State University College of Veterinary Medicine in a news release.
See N. Mammadova et al., “Lasting retinal injury in a mouse model of blast-induced trauma,” American Journal of Pathology, doi:10.1016/j.ajpath.2017.03.005, 2017.

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