Image of the Day: Embryoid

Using human pluripotent stem cells, scientists engineered an amniotic sac-like structure, potentially useful for uncovering the elusive cellular signals that lead to infertility.

By | August 11, 2017

A 3-D image stack, visualized by confocal microscopy, of a five-day-old human embryoid, made up of squamous amnion cells (green) and pluripotent cells (pink). Blue denotes nuclei.UNIVERSITY OF MICHIGANUsing human pluripotent stem cells and 3-D media, scientists have sparked the growth of an amniotic sac-like structure—“a hollow cyst, which contains a cavity (a lumen) that is enveloped by a layer of cells,” describes co-lead author Yue Shao in an email to The Scientist. They’ve dubbed it a post-implantation amniotic sac embryoid, PASE for short.

See Y. Shao et al., “A pluripotent stem cell-based model for post-implantation human amniotic sac development,” Nature Communications8:208, 2017.

Add a Comment

Avatar of: You



Sign In with your LabX Media Group Passport to leave a comment

Not a member? Register Now!

LabX Media Group Passport Logo


Avatar of: Barry@DataSense


Posts: 24

August 11, 2017

Surely there are more 'deserving' research projects on which to devote the dwindling research budget - after all we have enough people on the planet!

Popular Now

  1. 2017 Top 10 Innovations
    Features 2017 Top 10 Innovations

    From single-cell analysis to whole-genome sequencing, this year’s best new products shine on many levels.

  2. Thousands of Mutations Accumulate in the Human Brain Over a Lifetime
  3. Antiviral Immunotherapy Comes of Age
    News Analysis Antiviral Immunotherapy Comes of Age

    T-cell therapies are not just for cancer. Researchers are also advancing immunotherapy methods to protect bone marrow transplant patients from viral infections. 

  4. Search for Life on the Red Planet