Researchers examine the effects on the fruit fly intestine of the protein responsible for Fragile X syndrome in humans.
December 7, 2017|
ARTHUR LUHUR, INDIANA UNIVERSITYFragile X syndrome is caused by a mutation in a single gene, which encodes Fragile X mental retardation protein. Scientists have taken a close look at how this protein affects tissue growth, finding that it limits the expansion of a stem cell population during intestinal growth in Drosophila flies.
A. Luhur et al., "Opposing post-transcriptional control of InR by FMRP and LIN-28 adjusts stem-cell based tissue growth," Cell, doi:10.1016/j.celrep.2017.11.0