Researchers used light-sheet microscopy to form 3-D images of the process in primary cortical neurons from embryonic rats.
A combination of imaging techniques allows researchers to observe subcellular processes within organisms.
February 5, 2018|
TSUNG-LI LIU ET AL.
Researchers report in bioRxiv that they combined lattice light sheet microscopy, which increases the speed of image acquisition and reduces phototoxic damage to cells, with two-channel adaptive optics to image multiple cellular processes in vivo. Here, cells divide in a 1-micrometer-thick slab of a zebrafish eye.
T. Liu et al., “Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms,” bioRxiv, doi:10.1101/243352, 2018.