Prominent Neuroscientist Fired by Columbia, HHMI

The specific reason for Thomas Jessell’s dismissal has not been disclosed.

By Shawna Williams | March 8, 2018

Columbia University libraryPUBLICDOMAINPICTURES, GEORGE HODANUpdate (March 13): STAT News reports that some current and former Columbia students and postdocs have signed a petition urging the university to be more transparent about Jessell's infractions, and to put in place stronger protections for graduate students and postdocs.

Columbia University removed neuroscientist Thomas Jessell from his posts yesterday (March 7), The New York Times reports. The university says in a statement that “[t]hese decisions follow an investigation that revealed serious violations of University policies and values governing the behavior of faculty members in an academic environment,” but did not specify the nature of the violations. The Howard Hughes Medical Institute (HHMI), which had employed Jessell as an investigator since 1985, has also terminated him, according to Science.

Jessell is known for his work on how neurons control movement, according to the Times. He co-directed Columbia’s Kavli Institute and its Mortimer B. Zuckerman Mind Brain Behavior Initiative (MBBI) and was a past winner of the Kavli Prize for Neuroscience. Science notes that one of his former trainees, Marc Tessier-Lavigne, is now president of Stanford University.

As for Jessell's lab, the university’s statement says it “will fulfill its responsibility to close the lab in a manner that both preserves valuable research and helps those involved to continue to pursue their careers.”

Correction (March 9): The original version of this article cited information from the Columbia Daily Spectator that the future of the MBBI is in doubt as a result of Jessell's departure. According to a Columbia spokesperson, that information is not correct. It has been removed from the Daily Spectator's article. The Scientist regrets the error.

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Avatar of: James V. Kohl

James V. Kohl

Posts: 532

March 14, 2018

Jessell is the serior author of: Activity Regulates the Incidence of Heteronymous Sensory-Motor Connections

The positioning of newly born neurons is a tightly regulated process that is critical for the assembly of the nervous system. In the spinal cord, nuclear organization of motor neurons into pools is an elaborated morphogenetic feature at the basis of the wiring of spinal sensory motor circuits (Sürmeli et al., 2011, Hinckley et al., 2015, Bikoff et al., 2016). The events controlling motor neuron positioning during development have yet to be clearly defined.

The activity is food energy-dependent and RNA-mediated in the context of the physiology of pheromone-controlled reproduction, which biophysically constrains viral latency in species from microbes to humans. 

That fact suggests Jessell's termination occurred due to his ongoing failure to link the virus-driven degradation of messenger RNA to loss of motor control in all neurodegenerative diseases.  See for comparison: "Blood Music" (1985) by Greg Bear, who presciently linked energy-dependent changes in the microRNA/messenger RNA balance to the creation of an advanced human species.

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