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Graphic depicting the microbiota consisting of various blue and red bacterial cells
Boosting Bacterial Genomes to Better Explore the Microbiome
Aparna Nathan, PhD | Jun 7, 2024 | 4 min read
Gang Fang’s new metagenomics method helps sequence rare bacteria.
Spherical viruses with spiked membrane proteins on their surfaces surround larger suspended cancer cells. 
Introduction to Oncolytic Virotherapy 
Amielle Moreno, PhD | 8 min read
Oncolytic virotherapy selectively attacks tumors and triggers both immediate and long-lasting immune responses. 
A 3D microscopic image of a heart tissue section with cardiac myocytes and macrophages.
Taking Out the Trash: An Alternative Cellular Disposal Pathway
Charlene Lancaster, PhD | Jun 6, 2024 | 4 min read
Researchers reveal that cellular secretion removes defective mitochondria when lysosomes are dysfunctional.
Cartoon of clock faces arranged in the shape of a brain.
Human Neurons Play the Waiting Game
Shelby Bradford, PhD | Jun 5, 2024 | 4 min read
When it comes to development, an epigenetic clock may be responsible for human neurons’ slower maturation.
Modeling the Intestines with Mini Guts
Modeling the Intestines with Mini Guts
The Scientist Staff | 1 min read
In this webinar, Arthur Beyder and Melanie Maya Kaelberer will discuss how scientists use intestinal organoids, also known as mini guts, to explore the digestive system in health and disease.
Four circular maps of color-coded immune cell types corresponding to the four tumor microenvironment archetypes.
A Bird’s Eye View of the Tumor Microenvironment
Kamal Nahas, PhD | Jun 3, 2024 | 3 min read
Immune cells form different communities throughout a tumor, potentially disrupting how cancers respond to treatments.
Images of tumor organoids acquired using high-speed live cell interferometry.
Evaluating Tumor Heterogeneity with a High Throughput Pipeline
Charlene Lancaster, PhD | Jun 3, 2024 | 3 min read
An automated bioprinting and imaging platform allows researchers to examine heterogeneous responses to anticancer drugs within a tumor organoid population.
In situ hybridization procedure being conducted in a laboratory.
Tips and Tricks for In Situ Hybridization
Priyom Bose, PhD | 8 min read
In situ hybridization is a powerful molecular technique for detecting and localizing specific nucleic acids in cytological samples. 
Snake slithering across dirt. 
Snaking Towards Synthetic Antivenoms
Danielle Gerhard, PhD | May 31, 2024 | 6 min read
After more than a century of producing animal-based antivenoms, scientists turned to synthetic systems to develop safer and more effective snake bite treatments.
A 3D spherical neutrophil animation with a pink, polysegmented nucleus
The Nucleus’ Secret to Shapeshifting
Kamal Nahas, PhD | May 31, 2024 | 4 min read
Neutrophils contort their nuclei into various shapes by moderating one key regulatory protein previously shown to orchestrate DNA organization.
A person typing at a laptop computer, with a digital overlay showing multiple files coming together to a central point.
A Unifying Data Informatics Approach for Multimodal Research
The Scientist and Sapio Sciences | 4 min read
As drug research becomes more interdisciplinary, data informatics needs to keep up and accommodate a diverse array of inputs and requirements. 
Several X-shaped duplicated chromosomes floating on a blurry blue background.
Centromeres Mutate More Rapidly Than Expected
Kamal Nahas, PhD | May 30, 2024 | 4 min read
After sequencing centromeres in humans and other primates, researchers found that they vary greatly across species and potentially contribute to aging and disease.
A Hydractinia polyp with stinging cells shown in red throughout the body and the tentacles.
With Neither Brains nor Brawn, Jellyfish and Relatives Developed Subcellular Weapons Instead
Hannah Thomasy, PhD | May 29, 2024 | 6 min read
Anna Klompen explained how cnidarian stinging cells harpooned their way into her heart and could help answer fundamental questions in biology.
Harnessing Metagenomics for Health and Disease Research
Harnessing Metagenomics for Health and Disease Research
The Scientist Staff | 1 min read
Discover how metagenomics approaches provide insights into human diseases.
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