Studying tumor development and treatment in dogs and cats, in parallel with research on rodents and humans, could improve the successful translation of new cancer drugs.
In mice, malignant cells genetically modified to express an anticancer cytokine home in on tumors and reduce their growth.
A braided structure and some adhesive hydrogel make therapeutic microRNAs both stable and sticky.
Exosomes are emerging as key players in metastasis.
After surgery to remove a tumor, neutrophils recruited to the site spit out sticky webs of DNA that aid cancer recurrence.
Metastatic cancer cells use nanotubes to manipulate blood vessels.
Guts and Glory
An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.