Genetic Screens Provide Clues About Prognosis, Risk of Second Cancer
Mutations in the TP53 gene appear to influence the prognosis and likelihood of future cancers in pediatric leukemia patients.
Opinion: We Must Make Data More Accessible for Bioinformatics Training
In addition to programs geared towards transforming biologists into bioinformaticians, students need more raw material available for their education.
Extracting Exosomes to Detect Signs of Cancer in Urine
A new device uses anchored nanowires to capture extracellular vesicles from pee for microRNA analysis.
Chromosomal Instability Drives Cancer Metastasis
In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.
Boosting Immunotherapy Treatments in Mouse Colon Cancer
Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.
Mutant RAS Proteins Team Up for Oncogenicity
Mice with cancer whose KRAS proteins couldn’t link together had much better survival outcomes than those whose oncogenic mutant paired with wild-type KRAS.
Cancer Evolutionist: A Profile of Charles Swanton
Motivated by his father’s cancer diagnosis, the Francis Crick Institute cancer geneticist has been revealing the ways tumors evolve and why they are so difficult to treat.