Most reagents used for reducing disulfide bonds in peptides and proteins have unpleasant odors. To combat this problem, Pierce Chemical Co. of Rockford, Ill., has covalently attached the odorless reducing agent TCEP to an agarose support. Pierce's Immobilized TCEP Disulfide Reducing Gel allows reductions to be performed on the bench-top without the need for a fume hood and avoids the need for dialysis or gel filtration to remove the reducing reagent.

Pierce Chemical Co.
+1 (800) 874-3723

Courtesy of Sigma-Aldrich

Sigma-Aldrich's EZview affinity beads

A Colorful Solution

St. Louis-based Sigma-Aldrich has developed the EZview™ line of affinity beads for use in immunoprecipitation experiments. EZview resins are composed of red-colored agarose beads that increase the visibility of pellets, helping users avoid accidental aspiration of bound protein during centrifugation and washing steps. EZview resins are available for immunoprecipitation (Protein A and Protein G) applications and for affinity capture of FLAG®...

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