Brain Circuitry for Fear and Anxiety Is the Same on fMRI

A study in people fails to detect differences in the brain’s response to fear or anxiety, long thought to be controlled by different neural circuits.

amanda heidt
| 5 min read
fear, anxiety, fMRI, study, neural circuits, brain study, neuroscience, amygdala, BNST

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A prevailing belief in neuroscience has long been that fear and anxiety are distinct emotions, prompted by different stimuli that in turn activate different regions of the brain. Fear is a more basal response to an immediate threat thought to be controlled by the amygdala, while anxiety, linked to a part of the brain known as the bed nucleus of the stria terminalis, or BNST, plays out over time and doesn’t always stem from obvious danger.

Scientists are now challenging the belief that the two emotions are segregated in the brain. A study published September 21 in The Journal of Neuroscience demonstrates that when people are subjected to a certain threat meant to prompt fear or an uncertain threat that evokes anxiety, their brains seem to react the same, calling upon both the amygdala and the BNST in their response. While fear and anxiety are distinct ...

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Meet the Author

  • amanda heidt

    Amanda Heidt

    Amanda was an associate editor at The Scientist, where she oversaw the Scientist to Watch, Foundations, and Short Lit columns. When not editing, she produced original reporting for the magazine and website. Amanda has a master's in marine science from Moss Landing Marine Laboratories and a master's in science communication from UC Santa Cruz.
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