Interdisciplinary Research
These papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool http://www.facultyof1000.com.G. Hutvágner et al., "Sequence-specific inhibition of small RNA function," PLoS Biol, 2:E98, April, 2004.Hutvágner et al. have shown that 2'-O-methyl oligonucleotides stoichiometrically and irreversibly inhibit the activity of [microRNAs and small interfering RNAs], paving the way for rapid evaluation of their in vivo functions. Further, they
The Scientist Staff
Jun 6, 2004
These papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool
G. Hutvágner et al., "Sequence-specific inhibition of small RNA function,"
Hutvágner et al. have shown that 2'-O-methyl oligonucleotides stoichiometrically and irreversibly inhibit the activity of [microRNAs and small interfering RNAs], paving the way for rapid evaluation of their in vivo functions. Further, they use a 2'-O-methyl oligonucleotide targeted against the
X.M. Sun et al., "Caspase activation inhibits proteasome function during apoptosis,"
This paper reports a novel finding that the proteasome is inactivated by caspases at an early stage of apoptosis, which provides feed-forward amplification of apoptotic signals....
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