These papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool
B. Van den Berg et al., "X-ray structure of a protein-conducting channel,"
The first crystal structure of a protein translocation channel demonstrates the principle according to which proteins are funneled across membranes. The pore has an hourglass shape with a "plug" in the middle that probably swings out of the way when a protein is transported across.
A. Zeytun et al., "Fluorobodies combine GFP fluorescence with the binding characteristics of antibodies,"
Diverse, antibody-derived binding loops were inserted into four surface loops of a modified form of GFP, creating a library of potential binding agents that was screened successfully by phage display against a number of protein targets. High-specificity and high-affinity fluorescent binding proteins...