T. Söllner, M.K. Bennett, S.W. Whiteheart, R.H. Scheller, J.E. Rothman, "A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vessel docking, activation, and fusion," Cell, 75:409-18, 1993. (Cited in more than 100 publications through August 1995)
This paper describes the components of an in vitro pathway that are likely to correspond to those involved in the docking and fusion of vesicles," comments Thomas Söllner, an assistant laboratory member in the laboratory of James Rothman at Memorial Sloan-Kettering Cancer Center in New York City.
Comments by Thomas Söllner, Memorial Sloan-Kettering Cancer Center, New York
TO TRAP A SNAP: In their paper, Thomas Söllner and his colleagues assigned functions to previouslly identified components of a transport pathway between various cellular compartments.
This paper describes the components of an in vitro pathway that are likely to correspond to those involved in the docking and fusion of vesicles," comments Thomas Söllner, an assistant laboratory member in the laboratory of James Rothman at Memorial Sloan-Kettering Cancer Center in New York City.
Vesicles, Söllner explains, are the primary mediators of "the transfer of cargo between different compartments in eukaryotic cells. For example, in the secretory pathway,...
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