A whole menagerie of animals (including sheep, mice, cattle, goats and pigs) have been cloned by transfer of nuclear genetic material into an enucleated cell. Now, in an Advanced Online Publication from Nature,Taeyoung Shin and colleagues demonstrate that cats (Felis domesticus) can be cloned too (Nature 2002, DOI: 10.1038/nature723).Shin et al. isolated fibroblasts from the oral mucosa of an adult male cat or primary cumulus cell cultures and fused them with enucleated cat ova; they then implan
A whole menagerie of animals (including sheep, mice, cattle, goats and pigs) have been cloned by transfer of nuclear genetic material into an enucleated cell. Now, in an Advanced Online Publication from
Shin
Now that they can be cloned, cats may prove to have many more than nine ...
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Explore emerging mechanisms of immune checkpoint inhibitor resistance in hepatocellular carcinoma (HCC) and how combination immunotherapy strategies may improve antitumor immune responses and patient-specific treatment approaches.
Learn practical strategies for optimizing sample preparation, fragmentation, library construction, and quality control to generate high-quality next-generation sequencing (NGS) data across a range of sample types.
Learn how bulk T-cell receptor (TCR) repertoire sequencing can reveal clonotype diversity, support immune monitoring, and generate biological insights for translational immunology and biomarker discovery.
Explore how single-cell genotype-to-phenotype mapping can reveal clonal architecture and the functional consequences of somatic mutations in aging human tissues.
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