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Caloric restriction slows immune aging

Study finds that calorie-restricted rhesus monkeys have a higher percentage of naïve T cells

Cathy Tran
The link between caloric restriction and longevity may be mediated by reduced susceptibility to disease, researchers report this week in the Proceedings of the National Academy of Sciences. The scientists found that calorie-restricted older adult rhesus monkeys have at least 30% more naïve T cells than controls."This is the first study that shows caloric restriction maintains naïve T cells in primates," study co-author Ilhem Messaoudi of the Oregon National Research Primate Center told The Scientist.The link between calorie restriction and naïve T cells was previously demonstrated in mice by Richard Miller and his team at the University of Michigan."Some people said there's something special about short-lived animals and that this wouldn't work in humans," Miller, who was not involved in the monkey study, told The Scientist. "This is one of the very best pieces of evidence that show those doubters may be wrong. If it works in...

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