New virus behind cancer, MS?

After uncovering HPV's role in cancer, Harald zur Hausen is investigating another virus-disease relationship

Vicki Brower
Aug 17, 2010
Nobel Laureate linkurl:Harald zur Hausen;http://nobelprize.org/nobel_prizes/medicine/laureates/2008/hausen.html has a hunch, and he's gathering the data to support it.
Harald zur Hausen
Image: Wikimedia commons
For the past decade, zur Hausen and linkurl:Ethel-Michelle de Villiers,;http://www.dkfz.de/en/tumorvirus-charakterisierung/index.html his scientific partner and wife, are studying a little-known, single-stranded DNA virus -- Torque teno virus (TTV). Preliminary evidence is suggesting it may be an indirect cause or co-factor in certain multi-factorial diseases, including cancer and autoimmune diseases.Addressing 675 young scientists at last month's 60th Meeting of the Nobel Laureates in Lindau, Germany, zur Hausen presented new findings on TTV. He and de Villiers have identified viral proteins that resemble certain MS auto-antigens in brain lesions of patients with multiple sclerosis. He's also found segments of TTV genomes in many cancer cell lines, including leukemia and Hodgkin's lymphoma lines, with no similar patterns in normal human tissues. He's found relatively high levels of complete TTV sequences in gastrointestinal,...
The Scientist.Journal of Virology



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