Scientists from the Scripps Research Institute led by Geoffrey Chang have retracted three highly-cited papers (1, 2, 3) in Science on ATP binding cassette transporters, stating that new findings by another group invalidated their proposed structure and biology of the transporters. Two more retractions will appear in upcoming issues of the Journal of Molecular Biology and Proceedings of the National Academy of Science. The retracted papers span more than five years of work."I'm not sure there's ever been a retraction of this magnitude in the field," said Kasper Locher, a researcher and professor at the Institute of Molecular Biology and Biophysics in Switzerland, and an author of a September 2006 paper in Nature that illustrated major problems with Chang et al's findings. In an interview with The Scientist, Chang said he regretted any confusion his papers may have caused. "I deeply apologize to those...
suspicionsChristopher HigginsdoubtsNatureretraction email@example.com://www.scripps.edu/newsandviews/e_20010129/chang.htmlSciencehttp://www.the-scientist.com/pubmed/11546864Sciencehttp://www.the-scientist.com/pubmed/15890884Sciencehttp://www.the-scientist.com/pubmed/16373573Journal of Molcular Biologyhttp://www.the-scientist.com/pubmed/12823979http://www.the-scientist.com/pubmed/14970332http://www.the-scientist.com/pubmed/16943773The Scientisthttp://www.the-scientist.com/article/display/14257Christopher Higgins http://www.hgc.gov.uk/Client/Content.asp?ContentId=707Sciencehttp://www.the-scientist.com/pubmed/11546861Sciencehttp://www.the-scientist.com/pubmed/17185584
Interested in reading more?
Become a Member of
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!