Top 7 in cell biology

A snapshot of the most highly ranked articles in cell biology and related areas, from Faculty of 1000

Jef Akst
Jef Akst

Jef Akst is managing editor of The Scientist, where she started as an intern in 2009 after receiving a master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses.

View full profile.

Learn about our editorial policies.

linkurl:1. Cytokines, infection blockers; Patients infected by Candida albicans -- the causative agent of chronic mucocutaneous candidiasis disease (CMCD), an infection of the oral and genital mucosae, skin, and nails -- and possibly Staphylococcus aureus, often have mutations in genes encoding interleukin-17 receptor A (IL-17RA) and IL-17F, suggesting an essential role of these cytokines in protecting against such infections.A. Puel et al., "Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity," linkurl:Science,; 332:65-8, 2011. Evaluated by Dan Conrad, Virginia Commonwealth Univ; Jay Kolls, LSU Health Sciences Cen; Klaus Ley, La Jolla Inst for Allergy & Immunology; Sarah Gaffen, Univ Pitt; Joshua Milner, National Inst of Allergy and Infectious Diseases. linkurl:Free F1000 evaluation; linkurl:2. AMPK structure revealed; Researchers detail the crystal structure of AMP-activated protein kinase (AMPK), which helps regulate cell metabolism and has been implicated in diseases such as type 2 diabetes, obesity and...
B. Xiao et al., "Structure of mammalian AMPK and its regulation by ADP," linkurl:Nature,; 472:230-33, 2011. Evaluated by Chris Marshall and Mitsuhiko Ikura, Ontario Cancer Inst; Eduardo Rial, CSIC; Paul Clarke, Univ Dundee; John Kyriakis, Tufts Med Cen. linkurl:Free F1000 evaluation; linkurl:3. New nano-communication?;
Scanning electron micrographs of B. subtilis
Image: Courtesy of the Ben-Yehuda laboratory
G.P. Dubey and S. Ben-Yehuda, "Intercellular nanotubes mediate bacterial communication," linkurl:Cell,; 144:590-600, 2011. Evaluated by Ramanujam Srinivasan, Mithilesh Mishra and Mohan Balasubramanian, National Univ Singapore; Mélanie Hamon and Pascale Cossart, Institut Pasteur; Fabio Bagnoli and Rino Rappuoli, Novartis; Adrian Mehlitz and Roy Gross, Univ Würzburg. linkurl:Free F1000 evaluation; linkurl:4. A long-term memory chemical; A. Suzuki, et al., "Astrocyte-neuron lactate transport is required for long-term memory formation," linkurl:Cell,; 144:810-23, 2011. Evaluated by James Bamburg, Colo St Univ; David Wolfer, Univ Zurich; Faraz Sultan and David Sweatt, Univ Ala Birmingham; Karl-Peter Giese, King's Coll, UK. linkurl:Free F1000 evaluation; linkurl:5. Selfing RNA?; A. Wochner et al., "Ribozyme-catalyzed transcription of an active ribozyme," linkurl:Science,; 332:209-12, 2011. Evaluated by Yan Xu and Makoto Komiyama, Univ Tokyo; Peter Unrau, Simon Fraser Univ; Niles Lehman, Portland State Univ; Michael Yarus, Univ Colorado at Boulder; William Scott, Univ California at Santa Cruz. linkurl:Free F1000 evaluation; linkurl:6. Molding microtubules; C. elegansJ.S. Akella, et al., "MEC-17 is an alpha-tubulin acetyltransferase," linkurl:Nature,; 467:218-22, 2010. Evaluated by Carl Victor Lundin and Yanmin Yang, Stanford Univ Sch of Med; Mark Winey, Univ Colo; Hong-Wei Wang, Yale Univ. linkurl:Free F1000 evaluation; linkurl:7. Cell division with a twist; J. Guizetti et al., "Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments," linkurl:Science,; 331:1616-20, 2011. Evaluated by Martin Lowe, Univ Manchester; Roger Williams, MRC Laboratory of Molecular Biology; Christopher Janetopoulos, Vanderbilt Univ. linkurl:Free F1000 evaluation;

Interested in reading more?

Become a Member of

Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member?