Top 7 in cell biology

A snapshot of the most highly ranked articles in cell biology and related areas, from Faculty of 1000

Bob Grant
Bob Grant

From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer.

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linkurl:1. SWEET proteins found; A new class of proteins, dubbed SWEETs, function as glucose transporters, shuttling sugar molecules out of plant, worm and human cells. In some plants, SWEET proteins are co-opted by bacterial pathogens to deliver nutrition to the invaders.L.Q. Chen et al., linkurl:"Sugar transporters for intercellular exchange and nutrition of pathogens,"; __Nature__, 468:527-32, 2010. Evaluations by Julian Schroeder, UCSD; Akiko Sugio and Saskia Hogenhout, The John Innes Centre, UK; John Patrick, Univ Newcastle, Australia; David Alpers, Wash U Sch of Med; Bruno Stieger, Univ Hosp Zurich; Tapio Palva, Univ Helsinki; H Ekkehard Neuhaus, Univ Kaiserslautern, Germany. linkurl:Free F1000 Evaluation; linkurl:2. Codons boost protein expression; A library of more than 150 synthetic green fluorescent protein genes, inserted into E. coli DNA, showed that changing synonymous codons -- different nucleotide triplets that encode the same amino acid -- can alter protein expression up to 250-fold, likely a result of...
G. Kudla et al., linkurl:"Coding-sequence determinants of gene expression in Escherichia coli,"; __Science__, 324:255-58, 2009. Evaluations by Jonathan R Warner, Albert Einstein Coll of Med; Panayiotis Benos, Univ Pitt; Daniel Dykhuizen, Stony Brook; Jurg Bahler, UCL; Neeraj Dhar and John McKinney, EPFL, Switzerland; Audrey Gasch, Univ Wisc-Madison. linkurl:Free F1000 Evaluation;
Astrocyte with focal adhesion kinases
tagged green

Image: Neurorocker at en.wikipedia
linkurl:3. Focus on focal adhesions; P. Kanchanawong et al., linkurl:"Nanoscale architecture of integrin-based cell adhesions,"; __Nature__, 468:580-84, 2010. Evaluations by Martin Humphries, Univ Manchester; Herbert Schiller and Reinhard Fassler, Max Planck Gesellschaft, Germany; Ronen Zaidel-Bar, Nat Univ Singapore; John Couchman, Univ Copenhagen. linkurl:Free F1000 Evaluation; linkurl:4. The degradation trick; F. Zhang et al., linkurl:"Differential arginylation of actin isoforms is regulated by coding sequence-dependent degradation,"; __Science__, 329:1534-37, 2010. Evaluations by Sarah M P Jacobo and Andrius Kazlauskas, Harvard Med Sch; Jike Cui and Dennis Wall, Harvard Med Sch; Irina Kaverina, Vanderbilt Univ Med Cntr; Zhihua Li and Edward M Marcotte, Univ Texas. linkurl:Free F1000 Evaluation; linkurl:5. Fat rat daddies have diabetic daughters; S.F. Ng et al., linkurl:"Chronic high-fat diet in fathers programs beta-cell dysfunction in female rat offspring,"; __Nature__, 467:963-6, 2010. Evaluations by Russell Bonduriansky, Univ New South Wales, Australia; Enrico Avvedimento, Univ Federico II, Italy; Qingchun Tong and Perry Bickel, Univ Texas; Atsushi Iriki, RIKEN Brain Sci Inst, Japan; Mehboob Hussain, Johns Hopkins Univ; William H Colledge, Univ Cambridge. linkurl:Free F1000 Evaluation; linkurl:6. Shaping the ER; Y. Shibata et al., linkurl:"Mechanisms determining the morphology of the peripheral ER,"; __Cell__, 143:774-88, 2010. Evaluations by Charles Barlowe, Dartmouth Med Sch; Matthias Seedorf, Univ Heidelberg, Germany; Sascha Martens, Univ Vienna. linkurl:Free F1000 Evaluation; linkurl:7. The genome shuffle; P.J. Stephens et al., linkurl:"Massive genomic rearrangement acquired in a single catastrophic event during cancer development,"; __Cell__, 144:27-40, 2011. Evaluations by Jordi Camps and Thomas Ried, NCI/NIH; Yamini Dalal, NCI/NIH; Giovanni Neri, Univ Cattolica del S Cuore, Italy; Robert Booth, Virobay Inc; Yan Xu and Makoto Komiyama, Univ Tokyo. linkurl:Free F1000 Evaluation;

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