Top 7 in immunology

A snapshot of the most highly ranked articles in immunology and related areas, from Faculty of 1000

Edyta Zielinska
Mar 7, 2011
linkurl:1. Tracking B-cell movement;http://f1000.com/6837956?key=g8f7jn6yc79cycx By applying GFP technology in a new way, authors tracked B-cell maturation in the lymph nodes as the cells move from an area of rapid proliferation to an area where B cells that produce the best antibodies are selected, and back again, and found an essential role of T helper cells in this transition. G.D. Victora et al., "Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter," linkurl:__Cell,__;http://www.ncbi.nlm.nih.gov/sites/entrez/21074050?dopt=Abstract&holding=f1000%2Cf1000m 143:592-605, 2010. Evaluated by Jacques Deguine and Philippe Bousso, Inst Pasteur, France; Yinan Wang and Deepta Bhattacharya, Washington Univ in St. Louis; Naomi Harwood and Facundo Batista, London Res Inst, Cancer Res UK; Kai-Michael Toellner, Univ Birmingham, UK. linkurl:Free F1000 Evaluation;http://f1000.com/6837956?key=g8f7jn6yc79cycx linkurl:2. Worm infections;http://www.the-scientist.com/news/display/57957/ The first naturally occurring virus infection in C. elegans provides researchers with a genetically tractable model for studying virus-host interactions, innate immunity and the evolution of small RNA viral defenses.
Caenorhabditis...
M.A. F?lix et al., "Natural and experimental infection of caenorhabditis nematodes by novel viruses related to nodaviruses," linkurl:__PLoS Biol,__;http://www.ncbi.nlm.nih.gov/sites/entrez/21283608?dopt=Abstract&holding=f1000%2Cf1000m 9:e1000586, 2011. Evaluated by Benjamin Podbilewicz, Technion- Israel Inst of Tech, Israel; Jean-Luc Imler, Univ de Strasbourg, France; Morris F Maduro, Univ California Riverside. linkurl:Free F1000 Evaluation;http://f1000.com/8024962?key=z0zwwm87jw42ztf linkurl:3. Immune battle by suicide;http://f1000.com/6275956?key=3w8cs548zw610j1 E.A.Miao et al., "Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria," linkurl:__Nat Immunol,__;http://www.ncbi.nlm.nih.gov/sites/entrez/21057511?dopt=Abstract&holding=f1000%2Cf1000m 11:1136-42, 2010. Evaluated by Sun Mi Choi and Jay Kolls, Lousianna State Univ Health Sci Cen; Volker Briken and David Mosser, Univ of Maryland; Jordan Wesolowski and Fabienne Paumet, Jefferson Medical College; Sebastian Winter and Andreas Baumler, Univ of California, Davis; Nobuhiko Kayagaki, Kim Newton and Vishva Dixit, Genentech. linkurl:Free F1000 Evaluation;http://f1000.com/6275956?key=3w8cs548zw610j1 linkurl:4.Identifying the unknown;http://f1000.com/7792962?key=dx0nw38p878tf3l M.M. Reddy, et al., "Identification of candidate IgG biomarkers for Alzheimer's disease via combinatorial library screening," linkurl:__Cell,__;http://www.ncbi.nlm.nih.gov/sites/entrez/21215375?dopt=Abstract&holding=f1000%2Cf1000m 144:132-42, 2011. Evaluated by Angela Vincent, John Radcliffe Hosp, Univ Oxford; Robert Powers, University of Nebraska; Soumitra Ghosh and Kavita Shah, Purdue Univ; Ivan Gerling, Univ Tennessee Health Sci Cen; David Holtzman, Wash Univ School of Med. linkurl:Free F1000 Evaluation;http://f1000.com/7792962?key=dx0nw38p878tf3l linkurl:5. Mitochondria cause inflammation;http://f1000.com/2411956?key=twklz4nb2vf24wm Q. Zhang et al., "Circulating mitochondrial DAMPs cause inflammatory responses to injury," linkurl:__Nature,__;http://www.ncbi.nlm.nih.gov/sites/entrez/20203610?dopt=Abstract&holding=f1000%2Cf1000m 464:104-7, 2010. Evaluated by Ramzi Fattouh and John Brumell, The Hosp for Sick Children, Canada; Robert Sapolsky, Stanford Univ; Tullio Pozzan, Univ of Padova, Italy; Andrew S Neish, Emory Univ Sch Med; Rajarshi Mukherjee and David Criddle, Liverpool Univ, UK; George Hasko, Univ Med and Dentistry of New Jersey. linkurl:Free F1000 Evaluation;http://f1000.com/2411956?key=twklz4nb2vf24wm linkurl:6. IL-7 jump starts inflammation;http://f1000.com/8506956?key=y4cc31bm6t7t4c5 M. Pellegrini et al., "IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ Pathology," linkurl:__Cell,__;http://www.ncbi.nlm.nih.gov/sites/entrez/21295337?dopt=Abstract&holding=f1000%2Cf1000m 144:601-13, 2011. Evaluated by Raphaelle Parker and Irini Sereti, NIAID; Tobias Boettler and Matthias von Herrath, La Jolla Inst for Allergy and Immunology; Barry Rouse, Univ Tennessee. linkurl:Free F1000 Evaluation;http://f1000.com/8506956?key=y4cc31bm6t7t4c5 linkurl:7. Basophils not so necessary;http://f1000.com/5162972?key=22d99m8dpk8g055 C. Ohnmacht et al., "Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths," linkurl:__ Immunity,__;http://www.ncbi.nlm.nih.gov/sites/entrez/20817571?dopt=Abstract&holding=f1000%2Cf1000m 33(3):364-74, 2010. Evaluated by Avinash Bhandoola, Univ Penn; Luz Garcia-Hernandez, Javier Rangel-Moreno and Troy Randall, Univ Rochester; James Hewitson and Rick Maizels, University of Edinburgh, UK; Richard L Stevens, Brigham and Women's Hospital, Harvard Medical School; Daniel Mucida and Hilde Cheroutre, La Jolla Institute for Allergy & Immunology. linkurl:Free F1000 Evaluation;http://f1000.com/5162972?key=22d99m8dpk8g055



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