Top 7 in microbiology

A snapshot of the most highly ranked articles in microbiology and related areas, from Faculty of 1000

Jef Akst
Jef Akst

Jef Akst is managing editor of The Scientist, where she started as an intern in 2009 after receiving a master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses.

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linkurl:1. SWEET proteins found; new class of proteins, dubbed SWEETs, function as glucose transporters, shuttling sugar molecules out of plant, worm and human cells. In some plants, SWEET proteins are co-opted by bacterial pathogens to deliver nutrition to the invaders. L.Q. Chen et al., "Sugar transporters for intercellular exchange and nutrition of pathogens," linkurl:Nature,; 468:527-32, 2010. Evaluations by Heng-Cheng Hu and Caren Chang, Univ Maryland; Eric Van Der Graaff and Thomas Roitsch, Univ Graz; Michael Gjedde Palmgren, Univ Copenhagen; Giles Oldroyd, John Innes Cen; Julian Schroeder, UCSD; Akiko Sugio and Saskia Hogenhout, John Innes Cen; John Patrick, Univ Newcastle, Australia; David Alpers, Wash U Sch of Med; Bruno Stieger, Univ Hosp Zurich; Tapio Palva, Univ Helsinki; H Ekkehard Neuhaus, Univ Kaiserslautern, Germany. linkurl:Free F1000 Evaluation; linkurl:2. TRIMming retroviral infections;
A space-filling representation of a ubiquitin molecule
Image: Wikimedia commons, Rogerdodd
TRIM5, a ubiquitin ligase...
T. Pertel et al., "TRIM5 is an innate immune sensor for the retrovirus capsid lattice," linkurl:Nature,; 472:361-5, 2011. Evaluated by Qian Yin and Hao Wu, Weill Med Coll, Cornell Univ; Gijs Versteeg and Adolfo Garcia-Sastre, Mount Sinai School of Med; Vojo Deretic, Univ New Mexico. linkurl:Free F1000 evaluation; 3. Immune-driven tumorigenesis?S. Rakoff-Nahoum, R. Medzhitov, "Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88," linkurl:Science,; 317:124-7, 2007. Evaluated by Michelle Rooks and Wendy Garrett, Harvard ; Lora Hooper, UT Southwestern Med Cen, Maria Rescigno, European Inst Oncology; Patrick S Moore, Univ Pitt. linkurl:Free F1000 evaluation; 4. Glucose maintenanceD. Wu et al., "Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis," linkurl:Science,; 332:243-7, 2011. Evaluated by Thomas Nutman, NIH; Dhaya Seshasayee and Flavius Martin, Genentech; Alberto Mantovani, Istit Clinico Humanitis, Univ Milan. linkurl:Free F1000 evaluation; 5. Worm healing details revealedM.J. Broadhurst et al., "IL-22+ CD4+ T cells are associated with therapeutic trichuris trichiura infection in an ulcerative colitis patient," linkurl:Sci Transl Med,; 2:60ra88, 2010. Evaluated by Thirumalai Ramalingam and Thomas Wynn, NIH; Padraic Fallon, Trinity College Dublin; Dhaya Seshasayee and Flavius Martin, Genentech. linkurl:Free F1000 evaluation; 6. Microbiome masteryJ. Qin et al., "A human gut microbial gene catalogue established by metagenomic sequencing," linkurl:Nature,; 464:59-65, 2010. Evaluated by Michelle Rooks and Wendy Garrett, Havard; M?ire Begley and Paul Cotter, Teagasc; Andrew Anfora and Scott Lesley, Genomics Inst Novartis Res Found. linkurl:Free F1000 evaluation; 7. Picking a partnerM. Archetti, et al., "Let the right one in: a microeconomic approach to partner choice in mutualisms," linkurl:Am Nat,; 177:75-85, 2011. Evaluated by Zhanshan (Sam) Ma and Larry Forney, Univ Idaho. linkurl:Free F1000 evaluation;

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