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The Biggest DNA Origami Structures Yet
Abby Olena | Dec 6, 2017
Three new strategies for using DNA to generate large, self-assembling shapes create everything from a nanoscale teddy bear to a nanoscale Mona Lisa.
Clinical Trial Reporting for Pharma-Sponsored Trials Shows Improvement
Diana Kwon | Dec 4, 2017
The Good Pharma Scorecard finds some big pharmaceutical companies are meeting legal standards for disclosing results—but many studies still go unreported.
Partial Reprogramming Offers a Way to Generate High Volumes of Progenitor-Like Cells
Abby Olena | Nov 30, 2017
Activating genes for reprogramming factors for a short time transforms large numbers of differentiated cells into multipotent forms that could be useful for cell-based therapies.
Six-Letter DNA Alphabet Produces Proteins in Cells
Ruth Williams | Nov 29, 2017
Transcription and translation of DNA containing synthetic base pairs becomes a reality in living cells.
Immune Checkpoint Found Lacking in Type 1 Diabetes
Ruth Williams | Nov 15, 2017
Boosting levels of a the immunosuppressive protein PD-L1 in blood stem cells halts diabetes in a mouse model of the disease.
Researchers Build a Cancer Immunotherapy Without Immune Cells
Abby Olena | Nov 13, 2017
A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro.
Child Receives Transgenic Skin Over Most of His Body
Ruth Williams | Nov 8, 2017
A combination gene-and-cell therapy has given a boy with a grievous skin disease a new lease on life, and has resolved a dermatology debate to boot.
Hormone Loss Prevents Obesity and Diabetes in Mice
Abby Olena | Nov 6, 2017
Asprosin—involved in a rare disease called neonatal progeroid syndrome—targets neurons to stimulate appetite, and blocking the hormone wards off weight gain in rodents.
The Genetic Strategies of Dealing with High Altitude
Abby Olena | Nov 2, 2017
Andean highlander genomes possess cardiovascular-related variants, while populations from other regions evolved different solutions to manage the lack of oxygen.
Study Raises Questions About Brain Stimulation Boosting Memory
Ashley Yeager | Nov 1, 2017
In people with epilepsy, transcranial alternating current stimulation (tACS) does not affect memory-related brainwaves as widely claimed, researchers report.