To close out the year, in this issue on
But it has not all been plain sailing. Here is a selection of quotes that illustrate my top five grumbles, controversies, and setbacks of the year.
1. Let's start with a scalding comment on a hot area of research, systems biology from straight-talking Dutchman Ronald Plasterk: "The fundamental misconception of systems biology advocates is that one could create a 'virtual cell,' and use big computers to model life and make discoveries. ... a role. One makes discoveries by watching, working, checking. They want to be Darwin, but do not want to waste years on the