Is It Time to Rethink Parkinson’s Pathology?
Is It Time to Rethink Parkinson’s Pathology?
New evidence points to a waste-clearing problem in patients’ cells, rather than the accumulation of protein tangles, as the root cause of the neurodegenerative disease.
Is It Time to Rethink Parkinson’s Pathology?
Is It Time to Rethink Parkinson’s Pathology?

New evidence points to a waste-clearing problem in patients’ cells, rather than the accumulation of protein tangles, as the root cause of the neurodegenerative disease.

New evidence points to a waste-clearing problem in patients’ cells, rather than the accumulation of protein tangles, as the root cause of the neurodegenerative disease.

Features
Air Pollution May Damage People’s Brains
Air Pollution May Damage People’s Brains
Catherine Offord | Oct 1, 2019
Contaminants in the atmosphere appear to have harmful effects on neurodevelopment and cognitive function.
Why Immune Cells Extrude Webs of DNA and Protein
Why Immune Cells Extrude Webs of DNA and Protein
Borko Amulic, Gabriel Sollberger | Oct 1, 2019
Extracellular webs expelled by neutrophils trap invading pathogens, but these newly discovered structures also have ties to autoimmunity and cancer.
The Race to Nab Cheating Athletes
The Race to Nab Cheating Athletes
Anna Azvolinsky | Sep 1, 2019
Anti-doping organizations are constantly developing new tests to catch athletes trying to boost their performance in increasingly sophisticated ways.
Recent Trials for Fragile X Syndrome Offer Hope
Recent Trials for Fragile X Syndrome Offer Hope
Randi Hagerman | Sep 1, 2019
Despite a solid understanding of the biological basis of fragile X syndrome, researchers have struggled to develop effective treatments.
Neanderthal DNA in Modern Human Genomes Is Not Silent
Neanderthal DNA in Modern Human Genomes Is Not Silent
Jef Akst | Sep 1, 2019
From skin color to immunity, human biology is linked to our archaic ancestry.
Personalized Cancer Vaccines in Clinical Trials
Personalized Cancer Vaccines in Clinical Trials
Jasreet Hundal, Elaine R. Mardis | Jul 15, 2019
The field is young, but predicting antigens produced by patients’ malignant cells could yield successful treatments for individuals with a range of cancer types.
How the Microbiome Influences Drug Action
How the Microbiome Influences Drug Action
Shawna Williams | Jul 15, 2019
Through their effects on metabolism and immunity, bacteria in the gut affect whether medications will be effective for a given patient.
N-of-1 Trials Take on Challenges in Health Care
N-of-1 Trials Take on Challenges in Health Care
Catherine Offord | Jul 15, 2019
From personalizing clinical practice to aiding biomedical research, individualized clinical trials have been heralded as a solution to several problems plaguing modern medicine. But they’ve yet to be widely adopted.  
Quantum Biology May Help Solve Some of Life’s Greatest Mysteries
Quantum Biology May Help Solve Some of Life’s Greatest Mysteries
Catherine Offord | Jun 1, 2019
From the remarkable speed of enzyme-catalyzed reactions to the workings of the human brain, numerous biological puzzles are now being explored for evidence of quantum effects.