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The Philadelphia Family Helping to Drive Research on MLD
Catherine Offord | May 1, 2018
Though Calliope Joy’s disease is too far progressed to be treatable, her parents have helped other children with metachromatic leukodystrophy get access to an experimental therapy.
Slow March Toward a Canavan Cure
Ashley Yeager | May 1, 2018
Two decades after a successful crowdfunding campaign, some clinical trial patients have seen improvements—but there’s still no approved treatment for the disease.
Macrophages Play a Double Role in Cancer
Amanda B. Keener | Apr 1, 2018
Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.
Perineuronal Nets: A Mechanism to Control Brain Plasticity
Daniela Carulli | Apr 1, 2018
The neuronal coverings that mediate synaptic changes are involved in everything from memory to psychiatric disorders, affecting autism, Alzheimer’s, and addiction.
Researchers Getting Smarter About Pairing Cancer Treatments
Anna Azvolinsky | Apr 1, 2018
Multidrug combinations lead to better results for cancer patients, but efficiently identifying them is proving difficult.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
Paleoproteomics Opens a Window into the Past
Catherine Offord | Mar 1, 2018
Researchers are looking to proteins to explore the biology of ancient organisms, from medieval humans all the way back to dinosaurs.
Are the Brains of Transgender People Different from Those of Cisgender People?
Shawna Williams | Mar 1, 2018
Research into the biological basis of gender identity is in its infancy, but clues are beginning to emerge.
How Manipulating the Plant Microbiome Could Improve Agriculture
Davide Bulgarelli | Feb 1, 2018
It has become increasingly evident that, like animals, plants are not autonomous organisms but rather are populated by a cornucopia of diverse microorganisms.
Researchers Learn from Plant Viruses to Protect Crops
Claire Asher | Feb 1, 2018
Plants are locked in an ancient arms race with hostile viruses, but genome editing is giving crops the upper hand.