Opening a Can of Worms
Bob Grant | Feb 1, 2011
A father’s determination to help his son resulted in an experimental treatment for autism that uses roundworms to modulate inflammatory immune responses. Can the worms be used to treat other diseases?
Face to Face with the Emotional Brain
Ahmad R. Hariri & Paul J. Whalen | Feb 1, 2011
Amygdala responses to the facial signals of others predict both normal and abnormal emotional states. An understanding of the brain chemistry underlying these responses will lead to new strategies for treating and predicting psychopathology.
The Genes of Parkinsonā€™s Disease
Bobby Thomas and M. Flint Beal | Feb 1, 2011
The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure.
Mining Bacterial Small Molecules
L. Caetano M. Antunes, Julian E. Davies and B. Brett Finlay | Jan 1, 2011
As much as rainforests or deep-sea vents, the human gut holds rich stores of microbial chemicals that should be mined for their pharmacological potential.
From Simple To Complex
Jef Akst | Jan 1, 2011
The switch from single-celled organisms to ones made up of many cells has evolved independently more than two dozen times. What can this transition teach us about the origin of complex organisms such as animals and plants?
The Coming Health Crisis
Samuel S. Myers and Aaron Bernstein | Jan 1, 2011
Indirect effects of global climate change threaten the health of hundreds of millions of people. The very uncertainty that shrouds this issue must serve as an organizing principle for adaptation to its ill effects.
Mafia Wars
Jef Akst | Jun 1, 2010
An increasing amount of data is showing that the cellular battle between pathogens and hosts needs much more than a simple military metaphor to describe it—think undercover infiltration, front organizations, and forced suicide.