Hemoglobin C alleles are associated with protection from malaria in West Africa.
The human genome is under continuous selective pressure for resistance to infectious diseases. Several polymorphic alleles have been associated with resistance to malaria in West African populations, for example. In the November 15
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The authors predict that the HbC alleles will spread across Africa, replacing the sickle hemoglobin (hemoglobin S; HbS) polymorphisms that are associated with reduced fitness.
A citizen science game explores how social choices and networks can influence how an illness moves through a population.
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