M.X. Tang, D. Jacobs, Y. Stern, K. Marder, P. Schofield, B. Gurland, H. Andrews, R. Mayeux, "Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease," Lancet, 348:429-32, 1996. (Cited more than 127 times since publication)
Comments by Ming-Xin Tang, professor of biostatistics, Gertrude H. Sergievsky Center, Columbia University.
Alzheimer's disease, which is characterized by the progressive loss of cognitive function, afflicts about 5 percent to 10 percent of the elderly population in the United States. Although the U.S. Food and Drug Administration has approved some drugs for Alzheimer's, there is still no known effective treatment for the disease. However, a widely cited study by Ming-Xin Tang, a professor of biostatistics at Columbia University's Gertrude H. Sergievsky Center, has given hope that at least the onset of the disease can be delayed in postmenopausal women through the use of estrogen.
THE ESTROGEN EFFECT: Columbia...