For this article, Steve Bunk interviewed Rudolf Aebersold, cofounder, Institute for Systems Biology, Seattle. Data from the Web of Science (ISI, Philadelphia) show that Hot Papers are cited 50 to 100 times more often than the average paper of the same type and age.
S.P. Gygi, Y. Rochon, B.R. Franza, R. Aebersold, "Correlation between protein and mRNA abundance in yeast," Molecular and Cellular Biology, 19:1720-30, March, 1999. (Cited in 114 papers)
At virtually all levels of life sciences, from ecology to molecules, researchers today are intent on putting together the pieces. The aptly named Institute for Systems Biology (ISB) in Seattle was co-founded for just that purpose by this paper's senior author, Rudolf Aebersold. Another of ISB's three cofounders, Leroy Hood, had previously established the cross-disciplinary Department of Molecular Biotechnology at the University of Washington, where both men were professors before starting up ISB last year.
Interested in reading more?
Become a Member of
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!