Gene Therapy
Y.P. Yang, F.A. Nunes, K. Berencsi, E. Gonczol, J.F. Engelhardt, J.M. Wilson, "Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis," Nature Genetics, 7:362-9, 1994. (Cited in more than 75 publications as of April 1996) Comments by James M. Wilson, University of Pennsylvania VIRUS BASHER: Penn's James Wilson limits the mouse immune reaction when testing gene therapy for cystic firbrosis. His technique: Cripple the viral vector. The first
The Scientist Staff
Y.P. Yang, F.A. Nunes, K. Berencsi, E. Gonczol, J.F. Engelhardt, J.M. Wilson, "Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis," Nature Genetics, 7:362-9, 1994. (Cited in more than 75 publications as of April 1996)
Comments by James M. Wilson, University of Pennsylvania
 VIRUS BASHER: Penn's James Wilson limits the mouse immune reaction when testing gene therapy for cystic firbrosis. His technique: Cripple the viral vector. |
However, about a week after therapy was given and the gene-carrying virus delivered its load,...
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