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Molecular Biology

A. Simeone, D. Acampora, V. Nigro, A. Faiella, M. D'Esposito, A. Stornainolo, et al., "Differential regulation by retinoic acid of the homeobox genes of the four HOX loci in human embryonal carcinoma cells," Mechanisms of Development, 33:215-228, 1991. Edoardo Bonicelli (H. S. Raffaele, Istituto di Ricovero e Cura a Carattere Scientifico, Milan, Italy): "This paper put some order into the zoo of vertebrate homeobox genes controlling positional information necessary for the appropriate body s

The Scientist Staff

A. Simeone, D. Acampora, V. Nigro, A. Faiella, M. D'Esposito, A. Stornainolo, et al., "Differential regulation by retinoic acid of the homeobox genes of the four HOX loci in human embryonal carcinoma cells," Mechanisms of Development, 33:215-228, 1991.

Edoardo Bonicelli (H. S. Raffaele, Istituto di Ricovero e Cura a Carattere Scientifico, Milan, Italy): "This paper put some order into the zoo of vertebrate homeobox genes controlling positional information necessary for the appropriate body structures to develop along the major body axis. The process of putting these homeobox genes into order involved two steps.

"First, we completed the inventory of the existing 38 HOX genes, belonging to 13 homology groups and located in four genomic loci- -HOX1 to HOX4. In humans, HOX1 contains 11 genes found in 110 kilobases of chromosome 7; HOX2 contains nine genes in 100 kb of chromosome 17; HOX3 contains nine genes in 120 kb of chromosome...

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