Edited by: Paul Smaglik
Z. Liu, H. Hsu, D.V. Goeddel, M. Karin, "Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis, while NF-[kappa]B activation prevents cell death," Cell, 87:565-76, 1996. (Cited more than 70 times through November 1997)
Comments by Michael Karin, Department of Pharmacology, Program in Biomedical Sciences, School of Medicine, University of California, San Diego
SIGNAL DISSECTION: Michael Karin and colleagues picked apart the steps in TNF receptor 1 signaling to reveal three separate but interrelated pathways.